On our new variation graph release, codename Ghizzano v1.35.0, we made some improvements to our mappers, mpmap and giraffe, to improve speed and sensitivity.

We’ve also improved the usability of our transcriptomics analysis: We can produce more realistic simulated RNA-seq reads, vg rna can use GBWT haplotypes as reference paths and can create a spliced pangenome graph and pantranscriptome with chopped nodes.

Please check it out here: https://github.com/vgteam/vg/releases/tag/v1.35.0 

Contact us https://cglgenomics.ucsc.edu/contact-us/ to share feedback.